pimpinellin CAS 131-12-4

Introduction：Basic information about pimpinellin CAS 131-12-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

pimpinellin Basic information

• Product Name: pimpinellin
• Synonyms: 5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one;Pimpinecilin;5,6-dimethoxyfuro[2,3-h]chromen-2-one;5,6-DiMethoxy-2H-furo[2,3-h]chroMen-2-one;2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-;inhibit,Apoptosis,pimpinellin,Inhibitor
• CAS: 131-12-4
• MF: C13H10O5
• MW: 246.22
• Mol File: 131-12-4.mol

pimpinellin Chemical Properties

• Melting point: 119°
• Boiling point: 441.0±45.0 °C(Predicted)
• density: 1.352±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: powder
• color: Yellow
• InChI: InChI=1S/C13H10O5/c1-15-11-7-3-4-9(14)18-10(7)8-5-6-17-12(8)13(11)16-2/h3-6H,1-2H3
• InChIKey: BQPRWZCEKZLBHL-UHFFFAOYSA-N
• SMILES: C1(=O)OC2C3C=COC=3C(OC)=C(OC)C=2C=C1
• LogP: 1.477 (est)

Safety Information

• WGK Germany: WGK 3
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 2 Dermal Acute Tox. 2 Inhalation Acute Tox. 2 Oral
• Hazardous Substances Data: 131-12-4(Hazardous Substances Data)

pimpinellin Usage And Synthesis

Chemical Properties

Light yellow needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Radix Angelicae Pubescentis.

Uses

GABA receptor antagonist, phototoxin

Definition

ChEBI: Pimpinellin is a furanocoumarin.

Biological Activity

Pimpinellin is a coumarin isolated from roots of Angelica dahurica and Zosima absinthifolia th at exhibits anti-tumor, anti-allergic, antioxidant and anticholinesterase activities. It appears to reduce the release of histamine, secretion of TBF-α, interleukin (IL)-1β and IL-4. Pimpinellin exhibits potent cytotoxic activities against MGC-803, PC3, and A375 cancer cell lines.