TRIFAROTENE CAS 895542-09-3

Introduction:Basic information about TRIFAROTENE CAS 895542-09-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

TRIFAROTENE Basic information

Product Name:TRIFAROTENE
Synonyms:CD-5789;TRIFAROTENE
CAS:895542-09-3
MF:C29H33NO4
MW:459.58
EINECS:
Product Categories:
Mol File:895542-09-3.mol

TRIFAROTENE Chemical Properties

Boiling point 641.9±55.0 °C(Predicted)
density 1.173±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka3.58±0.10(Predicted)
form Solid
color White to Off-White

Safety Information

TRIFAROTENE Usage And Synthesis

UsesTrifarotene, is a retinoic acid receptor (RAR) agonist.
Pharmaceutical ApplicationsTrifarotene, also known as CD5789, is a first-in-class selective agonist of the retinoic acid receptor (RAR)-γ for the treatment of acne vulgaris in patients 9 years of age and older. Although its exact mechanism of action is unknown, the drug is able to modulate the expression of genes associated with inflammation and epidermal proliferation and differentiation.
SynthesisSynthesis of TRIFAROTENE
    

TRIFAROTENE Preparation Products And Raw materials

Trifarotene CAS 895542-09-3
Hexafluorotitanic acid CAS 17439-11-1
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