CAS 96-23-1|1,3-Dichloro-2-propanol

Introduction：Basic information about CAS 96-23-1|1,3-Dichloro-2-propanol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles31
7. Synonyms

Common Name	1,3-Dichloro-2-propanol
CAS Number	96-23-1	Molecular Weight	128.985
Density	1.3±0.1 g/cm3	Boiling Point	174.3±0.0 °C at 760 mmHg
Molecular Formula	C₃H₆Cl₂O	Melting Point	-4 °C
MSDS	ChineseUSA	Flash Point	85.6±0.0 °C
Symbol	GHS06, GHS08	Signal Word	Danger

Names

Name	1,3-dichloropropan-2-ol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	174.3±0.0 °C at 760 mmHg
Melting Point	-4 °C
Molecular Formula	C₃H₆Cl₂O
Molecular Weight	128.985
Flash Point	85.6±0.0 °C
Exact Mass	127.979568
PSA	20.23000
LogP	0.66
Vapour Pressure	0.4±0.7 mmHg at 25°C
Index of Refraction	1.462
InChIKey	DEWLEGDTCGBNGU-UHFFFAOYSA-N
SMILES	OC(CCl)CCl
Water Solubility	soluble. >=10 g/100 mL at 23 ºC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB1400000

CHEMICAL NAME :: 2-Propanol, 1,3-dichloro-

CAS REGISTRY NUMBER :: 96-23-1

BEILSTEIN REFERENCE NO. :: 1732063

LAST UPDATED :: 199801

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C3-H6-Cl2-O

MOLECULAR WEIGHT :: 128.99

WISWESSER LINE NOTATION :: G1YQ1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 800 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4550 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 250 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,401,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5378 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 200 (estimated) No. of Female Employees: 6 (estimated)

Safety Information

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H312-H350
Precautionary Statements	P201-P280-P301 + P310-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R21;R25;R45
Safety Phrases	S53-S45-S36/37-S16
RIDADR	UN 2750 6.1/PG 2
WGK Germany	3
RTECS	UB1400000
Packaging Group	II
Hazard Class	6.1
HS Code	29055910

Customs

HS Code	2905590090
Summary	2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles31

Mechanism of chemical activation of sodium chloride in the presence of amino acids.

Food Chem. 166 , 301-8, (2014)

Sodium chloride has been shown to promote chlorination of glycerol during thermal processing. However, the detailed mechanism of this reaction is not well understood. Preliminary experiments have indi...

Exploring the enantioselective mechanism of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by iterative saturation mutagenesis.

Appl. Environ. Microbiol. 81(8) , 2919-26, (2015)

Halohydrin dehalogenase from Agrobacterium radiobacter AD1 (HheC) shows great potential in producing valuable chiral epoxides and β-substituted alcohols. The wild-type (WT) enzyme displays a high R-en...

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper desc...

Synonyms

1,3-dichloro-1,3-dideoxyglycerol

2-Propanol, 1,3-dichloro-

glycerol 1,3-dichlorohydrin

U 25,354

1,3-dichloro-2-hydroxypropane

EINECS 202-491-9

1,3-dichlorohydrin

DCP

gdch

1,3-DCP

Enodrin

1,3-di-chloro-2-propanol

1,3-dichloro-2-propyl alcohol

Dichlorohydrin

1,3-dichloropropan-2-ol

MFCD00000951

1,3-Dichloro-2-propanol

Glycerol-α,γ-dichlorohydrin

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