CAS 61036-62-2|Teicoplanin
Introduction：Basic information about CAS 61036-62-2|Teicoplanin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Teicoplanin | ||
|---|---|---|---|
| CAS Number | 61036-62-2 | Molecular Weight | 2526.73 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C130H175Cl2N9O37R6 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | Telicoplanin |
|---|---|
| Synonym | More Synonyms |
Teicoplanin BiologicalActivity
| Description | Teicoplanin is a semisynthetic glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Molecular Formula | C130H175Cl2N9O37R6 |
| Molecular Weight | 2526.73 |
| PSA | 662.41000 |
| LogP | 0.40 |
| Index of Refraction | 1.754 |
| InChIKey | BJNLLBUOHPVGFT-CAYRISATSA-N |
| SMILES | CCCCCCCCCC(=O)NC1C(Oc2c3cc4cc2Oc2ccc(cc2Cl)C(OC2OC(CO)C(O)C(O)C2NC(C)=O)C2NC(=O)C(NC(=O)C4NC(=O)C4NC(=O)C(Cc5ccc(c(Cl)c5)O3)NC(=O)C(N)c3ccc(O)c(c3)Oc3cc(O)cc4c3)c3ccc(O)c(c3)-c3c(OC4OC(CO)C(O)C(O)C4O)cc(O)cc3C(C(=O)O)NC2=O)OC(CO)C(O)C1O |
| Storage condition | 2-8℃ |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 14 mg/kg/31D-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Ear) - change in acuity
- REFERENCE :
- LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 1,613,1986
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| RTECS | WY1559000 |
Articles53
More Articles| Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus. Pak. J. Pharm. Sci. 26(2) , 383-9, (2013) In the present study a vancomycin resistant Staphylococcus aureus (S. aureus) (VRSA) (Labeled as CP2) was isolated from the blood of a post-operative cardiac patient is described. It harbors a plasmid... | |
| A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity. Sci. Transl. Med. 7 , 290ra89, (2015) Currently, no approved therapeutics exist to treat or prevent infections induced by Ebola viruses, and recent events have demonstrated an urgent need for rapid discovery of new treatments. Repurposing... | |
| Once-weekly dalbavancin versus daily conventional therapy for skin infection. N. Engl. J. Med. 370(23) , 2169-79, (2014) Dalbavancin, a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens, has a long plasma half-life, allowing for once-weekly dosing. DISCOVER 1 and DISCOVER 2 were identicall... |
Synonyms
| teichomycin |
| TEICOPLANIN |
| (1S,2R,19R,22R,34S,37R,40R,52R)-2-[(2-Acetamido-2-deoxy-β-D-glucopyranosyl)oxy]-22-amino-5,15-dichloro-64-{[2-(decanoylamino)-2-deoxy-β-D-glucopyranosyl]oxy}-26,31,44,49-tetrahydroxy-47-(α-D -mannopyranosyloxy)-21,35,38,54,56,59-hexaoxo-7,13,28-trioxa-20,36,39,53,55,58-hexaazaundecacyclo[38.14.2.2.2.2.1.1.1.1.0.0]hexahexaconta-3,
 5,8(64),9,11,14,16,23(61),24,26,29(60),30,32 |
| TEICOPLANIN,JP |
| Tagocid |
| TeicoplaninSodium |
| 8327a |
| TEIC |
| Teicoplanin(sterile,non-sterile) |
| antibiotic8327a |
| Teocoplanin |
