Introduction：Basic information about CAS 136132-68-8|PKC substrate (MBP), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].
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References
[1]. Durocher Y, et al. Activation of an 85 kDa ribosomal S6 kinase during serotonin-induced oocyte maturation. Int J Dev Biol. 1996 Jun;40(3):557-66.
[2]. Loog M, et al. Comparison of Substrate Specificities of Protein Kinases A and C Based on Peptide Substrates[J]. Bioorganic Chemistry, 1994, 22(3): 328-336.
A synthetic peptide substrate for selective assay of protein kinase C.
Biochem. Biophys. Res. Commun. 166 , 1220, (1990)
Among various phosphate acceptor proteins and peptides so far tested, a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, Gln-Lys-Arg-Pro-Ser(8)-Gln-Arg-Ser-Lys-Tyr-Leu...
