CAS 135701-67-6|(D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin

Introduction:Basic information about CAS 135701-67-6|(D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin
CAS Number135701-67-6Molecular Weight1248.436
Density1.5±0.1 g/cm3Boiling Point/
Molecular FormulaC57H89N19O13Melting Point/
MSDSUSAFlash Point/

Names

Name[D-Arg0,Hyp3,D-Phe7,Leu8]-Bradykinin
SynonymMore Synonyms

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Molecular FormulaC57H89N19O13
Molecular Weight1248.436
Exact Mass1247.688721
PSA533.80000
LogP-1.49
Index of Refraction1.681
InChIKeyIBUPLVFJDPVVRN-AFIJWGRYSA-N
SMILESCC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CC(O)CN1)C(=O)NC(CCCN=C(N)N)C(=O)OC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(N)CCCN=C(N)N

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Articles5

More Articles
New highly potent bradykinin B2 receptor antagonists.

Agents Actions 34 , 138-141, (1991)

pA2 values of new B2 receptor antagonists ranging from 7.51 to 8.86 were measured on the rabbit jugular vein, while lower values were observed in the other preparations (for instance, the hamster urin...

Non-selectivity of new bradykinin antagonists for B1 receptors.

Life Sci. 51 , PL 125, (1992)

Two new B1 receptor antagonists, [Hyp3,Thi5,DTic7,Oic8]desArg9-BK and DArg[Hyp3,Thi5,DTic7,Oic8]desArg9-BK were tested in vitro on the rabbit jugular vein and the guinea pig ileum (preparations contai...

A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers.

J. Med. Chem. 35 , 1563, (1992)

A systematic study on the dimerization of the bradykinin (BK) antagonist D-Arg0-Arg1-Pro2-Hyp3-Gly4-Phe5-Ser6-D-Phe 7-Leu8-Arg9 has been performed. The first part of this study involved compounds wher...

Synonyms

D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG
L-Ornithine, N-(diaminomethylene)-D-ornithyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-leucyl-N-(diaminomethylene)-
Leu(8)]-bradykinin B2
D-Arg-L-Arg-L-Pro-L-t4Hyp-Gly-L-Phe-L-Ser-D-Phe-L-Leu-L-Arg-OH
D-ARG-[HYP3,D-PHE7,LEU8]-BRADYKININ
H-D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG-OH
D-Arg(0)[Hyp(3),D-Phe(7),Leu(8)]-BK
D-Arg-L-Arg-L-Pro-4-Hydroxy-L-Pro-Gly-L-Phe-L-Ser-D-Phe-L-Leu-L-Arg-OH
Aaphgpspla
(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ
bradykinin,Arg-Hyp(3)-Phe(7)-Leu(8)
N-(Diaminomethylene)-D-ornithyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithine
D-Arg(0)[Hyp(3)
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