CAS 96990-18-0|Momordin Ic

Introduction：Basic information about CAS 96990-18-0|Momordin Ic, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Momordin Ic BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Momordin Ic
CAS Number	96990-18-0	Molecular Weight	764.939
Density	1.4±0.1 g/cm3	Boiling Point	886.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₁H₆₄O₁₃	Melting Point	/
MSDS	/	Flash Point	263.1±27.8 °C

Names

Name	(2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxane-2-carboxylic acid
Synonym	More Synonyms

Momordin Ic BiologicalActivity

Description	Momordin Ic is a principal saponin constituent of Fructus Kochiae, with with anti-cancer bioactivity. Momordin Ic induces apoptosis through oxidative stress-regulated mitochondrial dysfunction[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References	[1]. Mi Y, et al. Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways. Free Radic Biol Med. 2016 Jan;90:230-42. [2]. Wang J, et al. Suppressive effects of Momordin Ic on HepG2 cell migration and invasion by regulating MMP-9 and adhesion molecules: Involvement of p38 and JNK pathways. Toxicol In Vitro. 2019 Apr;56:75-83.

Description

Momordin Ic is a principal saponin constituent of Fructus Kochiae, with with anti-cancer bioactivity. Momordin Ic induces apoptosis through oxidative stress-regulated mitochondrial dysfunction[1][2].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer

References

[1]. Mi Y, et al. Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways. Free Radic Biol Med. 2016 Jan;90:230-42.

[2]. Wang J, et al. Suppressive effects of Momordin Ic on HepG2 cell migration and invasion by regulating MMP-9 and adhesion molecules: Involvement of p38 and JNK pathways. Toxicol In Vitro. 2019 Apr;56:75-83.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	886.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₁H₆₄O₁₃
Molecular Weight	764.939
Flash Point	263.1±27.8 °C
Exact Mass	764.434692
PSA	212.67000
LogP	9.87
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.606
InChIKey	HWYBGIDROCYPOE-WEAQAMGWSA-N
SMILES	CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(C(=O)O)C(O)C(OC7OCC(O)C(O)C7O)C6O)C(C)(C)C5CCC43C)C2C1

Safety Information

Safety Phrases	24/25

Synonyms

(3β)-28-Hydroxy-28-oxoolean-12-en-3-yl 3-O-β-D-xylopyranosyl-β-D-glucopyranosiduronic acid

oleanolic acid 3-O-monodesmoside

MomordinIc

X1188

Olean-12-en-28-oic acid, 3-[(3-O-β-D-xylopyranosyl-β-D-glucopyranuronosyl)oxy]-, (3β)-

Scoparianoside B

Momordin Ic

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