Introduction：Basic information about CAS 134052-73-6|(S)-4CPG, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (S)-4CPG |
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| CAS Number | 134052-73-6 | Molecular Weight | 195.17 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C9H9NO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (s)-4-carboxyphenylglycine |
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(S)-4CPG BiologicalActivity
| Description | (S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Neurological Disease |
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| References | [1]. Hayashi Y, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7. [2]. Fisher K, et al. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul;77(1):59-66. |
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Chemical & Physical Properties
| Molecular Formula | C9H9NO4 |
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| Molecular Weight | 195.17 |
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| Exact Mass | 195.05300 |
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| PSA | 100.62000 |
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| LogP | 1.16950 |
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| InChIKey | VTMJKPGFERYGJF-ZETCQYMHSA-N |
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| SMILES | NC(C(=O)O)c1ccc(C(=O)O)cc1 |
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