CAS 2557-49-5|Diflorasone

Introduction：Basic information about CAS 2557-49-5|Diflorasone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Diflorasone BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Diflorasone
CAS Number	2557-49-5	Molecular Weight	410.452
Density	1.4±0.1 g/cm3	Boiling Point	569.8±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₈F₂O₅	Melting Point	228-239ºC
MSDS	/	Flash Point	298.4±30.1 °C

Names

Name	diflorasone
Synonym	More Synonyms

Diflorasone BiologicalActivity

Description	Diflorasone is a potent topical anti-inflammatory steroid.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Wickrema Sinha AJ, et al. Percutaneous absorption and excretion of tritium-labeled diflorasone diacetate, a new topical corticosteroid in the rat, monkey and man. J Invest Dermatol. 1978 Dec;71(6):372-7.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	569.8±50.0 °C at 760 mmHg
Melting Point	228-239ºC
Molecular Formula	C₂₂H₂₈F₂O₅
Molecular Weight	410.452
Flash Point	298.4±30.1 °C
Exact Mass	410.190491
PSA	94.83000
LogP	1.61
Vapour Pressure	0.0±3.6 mmHg at 25°C
Index of Refraction	1.579
InChIKey	WXURHACBFYSXBI-XHIJKXOTSA-N
SMILES	CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO
Storage condition	Refrigerator

Safety Information

HS Code	2937229000

Customs

HS Code	2937229000

Synonyms

(6a,11b,16b)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16β)-

(6S,8S,9S,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

6a,9a-Difluoro-16b-methyl-d-1,4-pregnadiene-11b,17a,21-triol-3,20-dione

(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

Diflorasone

(6α,11β,16β)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-17-glycoloyl-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

diflorasonum [INN_la]

flumetasone

(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

6a,9a-Difluoro-16b-methylprednisolone

flumethasone

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