Introduction：Basic information about CAS 362-29-8|propiomazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | propiomazine |
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| CAS Number | 362-29-8 | Molecular Weight | 340.48200 |
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| Density | 1.137g/cm3 | Boiling Point | 500.8ºC at 760mmHg |
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| Molecular Formula | C20H24N2OS | Melting Point | / |
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| MSDS | / | Flash Point | 256.7ºC |
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Names
| Name | propiomazine |
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| Synonym | More Synonyms |
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propiomazine BiologicalActivity
| Description | Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia[1][2]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Histamine Receptor |
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| In Vivo | Propiomazine (0.2 mg/kg, nasal administration, rats) is quickly absorbed, followed by rapid reduction of the plasma concentrations[3]. Propiomazine (25 mg/kg, i.p., at 0 and 3 h after challenge) protects rats against CCl4-induced hepatic injury[4]. Propiomazine (0.31-20 mg/kg, i.v.) increases plasma prolactin concentrations in rats[5]. |
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Chemical & Physical Properties
| Density | 1.137g/cm3 |
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| Boiling Point | 500.8ºC at 760mmHg |
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| Molecular Formula | C20H24N2OS |
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| Molecular Weight | 340.48200 |
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| Flash Point | 256.7ºC |
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| Exact Mass | 340.16100 |
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| PSA | 48.85000 |
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| LogP | 4.89710 |
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| InChIKey | UVOIBTBFPOZKGP-UHFFFAOYSA-N |
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| SMILES | CCC(=O)c1ccc2c(c1)N(CC(C)N(C)C)c1ccccc1S2 |
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Synonyms
| Propiomazinum |
| 1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one |
| Propiomazinum [INN-Latin] |
| Propiomazina [INN-Spanish] |
| Wy-1359 |
| Largon |
| Dorevan |
| Phenoctyl |
| 1-[10-(2-dimethylamino-propyl)-10H-phenothiazin-2-yl]-propan-1-one |
| Propionylpromethazine |
| Propiomazina |
| 1-[10-(2-dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-one |
| 10-<2-Dimethylamino-propyl>-3-propionyl-phenothiazin |
| 3-Propionyl-10-<2-dimethylamino-propyl>-phenothiazin |
| 1-[10-(2-Dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-on |
