CAS 132202-29-0|D-Mannitol-13C

Introduction:Basic information about CAS 132202-29-0|D-Mannitol-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameD-Mannitol-13C
CAS Number132202-29-0Molecular Weight183.16400
Density/Boiling Point/
Molecular FormulaC6H14O6Melting Point167-170ºC(lit.)
MSDSUSAFlash Point/

Names

Name(2S,3S,4R,5R)-hexane-1,2,3,4,5,6-hexol
SynonymMore Synonyms

D-Mannitol-13C BiologicalActivity

DescriptionD-Mannitol-13C is the 13C labeled D-Mannitol[1][2][3][4].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>Metabolic Disease
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9.;Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal a

Chemical & Physical Properties

Melting Point167-170ºC(lit.)
Molecular FormulaC6H14O6
Molecular Weight183.16400
Exact Mass183.08200
PSA121.38000
InChIKeyFBPFZTCFMRRESA-CCCNNFAYSA-N
SMILESOCC(O)C(O)C(O)C(O)CO

Safety Information

RIDADRNONH for all modes of transport
WGK Germany3

Synonyms

D-Mannitol-1-13C
<1-13C>Mannitol
MFCD00084008
D-Mannitol-1-13C,1,1-d2
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