Introduction：Basic information about CAS 139954-00-0|Palbinone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Palbinone |
|---|
| CAS Number | 139954-00-0 | Molecular Weight | 358.47 |
|---|
| Density | 1.2±0.1 g/cm3 | Boiling Point | 508.5±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C22H30O4 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 275.4±26.6 °C |
|---|
Names
| Name | Palbinone |
|---|
| Synonym | More Synonyms |
|---|
Palbinone BiologicalActivity
| Description | Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
| Target | IC50: 46 nM (3α-HSD)[1] |
|---|
| References | [1]. Kadota S, et al. Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90. |
|---|
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|
| Boiling Point | 508.5±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C22H30O4 |
|---|
| Molecular Weight | 358.47 |
|---|
| Flash Point | 275.4±26.6 °C |
|---|
| Exact Mass | 358.214417 |
|---|
| PSA | 74.60000 |
|---|
| LogP | 3.35 |
|---|
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
|---|
| Index of Refraction | 1.586 |
|---|
| InChIKey | KIAKLFLISZCITK-PPAUHQMUSA-N |
|---|
| SMILES | CC1(C)C(O)CCC2(C)C1CCC1(C)C2C=CC2=C(O)C(=O)C(=O)C21C |
|---|
Synonyms
| 18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3β,5α)- |
| Gona-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,10,14-pentamethyl-, (3β,5α)- |
| (3β,5α)-3,17-Dihydroxy-4,4,8,10,14-pentamethylgona-11,13(17)-diene-15,16-dione |
