CAS 1362-42-1|(+)-absinthin
Introduction：Basic information about CAS 1362-42-1|(+)-absinthin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (+)-absinthin | ||
|---|---|---|---|
| CAS Number | 1362-42-1 | Molecular Weight | 496.635 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 700.6±60.0 °C at 760 mmHg |
| Molecular Formula | C30H40O6 | Melting Point | 165-166℃ (dec.) |
| MSDS | / | Flash Point | 230.8±26.4 °C |
Names
| Name | absinthin |
|---|---|
| Synonym | More Synonyms |
(+)-absinthin BiologicalActivity
| Description | Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Zhang W, et al. Total synthesis of absinthin. J Am Chem Soc. 2005 Jan 12;127(1):18-9. [2]. Lachenmeier DW, et al. Absinthe--a review. Crit Rev Food Sci Nutr. 2006;46(5):365-77. [3]. Talmon M, et al. Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+-shuttling event. J Biol Chem. 2019 Aug 16;294(33):12472-12482. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 700.6±60.0 °C at 760 mmHg |
| Melting Point | 165-166℃ (dec.) |
| Molecular Formula | C30H40O6 |
| Molecular Weight | 496.635 |
| Flash Point | 230.8±26.4 °C |
| Exact Mass | 496.282501 |
| PSA | 93.06000 |
| LogP | 2.41 |
| Vapour Pressure | 0.0±5.0 mmHg at 25°C |
| Index of Refraction | 1.609 |
| InChIKey | PZHWYURJZAPXAN-ILOFNVQHSA-N |
| SMILES | CC1=CC2C3C4C(=C(C)C3C13C1OC(=O)C(C)C1CCC(C)(O)C23)C1OC(=O)C(C)C1CCC4(C)O |
Synonyms
| Sbsinthin |
| (1R,2R,5S,8S,9S,12S,13R,14S,15S,16R,17S,20S,21S,24S)-12,17-Dihydroxy-3,8,12,17,21,25-hexamethyl-6,23-dioxaheptacyclo[13.9.2.0.0.0.0.0]hexacosa-3,25-diene-7,22-dione |
| ABSINTHII TINCTURA |
| ABSYNTHIN |
| Absinthiin |
| Absynthine |
| 2H-7,13b-Ethenofuro[2'',3'':4',5']azuleno[1',2':2,3]azuleno[4,5-b]furan-2,12(11H)-dione, 3,3a,4,5,6,6a,6b,7,7a,8,9,10,10a,13a,13c,14b-hexadecahydro-6,8-dihydroxy-3,6,8,11,14,15-hexamethyl-, (3S,3aS,6S,6aR,6bS,7S,7aR,8S,10aS,11S,13aS,13bR,13cR,14bS)- |
