CAS 338-95-4|9-fluoroprednisolone

Introduction:Basic information about CAS 338-95-4|9-fluoroprednisolone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name9-fluoroprednisolone
CAS Number338-95-4Molecular Weight378.435
Density1.4±0.1 g/cm3Boiling Point566.7±50.0 °C at 760 mmHg
Molecular FormulaC21H27FO5Melting Point274 - 275ºC
MSDS/Flash Point296.5±30.1 °C

Names

NameIsoflupredone
SynonymMore Synonyms

9-fluoroprednisolone BiologicalActivity

DescriptionIsoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
In VivoIsoflupredone shows a significant decrease in serum potassium level in horses. Isoflupredone is a potent drug for the treatment of recurrent airway obstruction affected horses[1].
References

[1]. Picandet V, et al. Comparison of efficacy and tolerability of isoflupredone and dexamethasone in the treatment of horses affected with recurrent airway obstruction ('heaves'). Equine Vet J. 2003;35(4):419-424.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point566.7±50.0 °C at 760 mmHg
Melting Point274 - 275ºC
Molecular FormulaC21H27FO5
Molecular Weight378.435
Flash Point296.5±30.1 °C
Exact Mass378.184265
PSA94.83000
LogP1.38
Vapour Pressure0.0±3.5 mmHg at 25°C
Index of Refraction1.600
InChIKeyWAIJIHDWAKJCBX-BULBTXNYSA-N
SMILESCC12C=CC(=O)C=C1CCC1C3CCC(O)(C(=O)CO)C3(C)CC(O)C12F
Storage condition2~8°C

Safety Information

Hazard CodesXi

Synonyms

Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy
9-fluoroprednisolone
1-Dehydro-9a-fluorohydrocortisone
(11b)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
9a-fluoroprednisolone
(11β)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
DELTAFLUDROCORTISONE
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-, (11β)-
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