Introduction：Basic information about CAS 61477-96-1|Piperacillin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Piperacillin |
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| CAS Number | 61477-96-1 | Molecular Weight | 517.555 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C23H27N5O7S | Melting Point | 139-140ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | piperacillin |
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| Synonym | More Synonyms |
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Piperacillin BiologicalActivity
| Description | Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. B. Holmes, et al. A Review of its Antibacterial Activity, Pharmacokinetic Properties and Therapeutic Use. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Melting Point | 139-140ºC |
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| Molecular Formula | C23H27N5O7S |
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| Molecular Weight | 517.555 |
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| Exact Mass | 517.163147 |
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| PSA | 181.73000 |
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| LogP | 1.88 |
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| Index of Refraction | 1.678 |
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| InChIKey | IVBHGBMCVLDMKU-GXNBUGAJSA-N |
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| SMILES | CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C2SC(C)(C)C3C(=O)O)c2ccccc2)C(=O)C1=O |
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| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XH8952200
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-6-(((((4-ethyl-2,3-dioxo- 1-piperazinyl)carbonyl)amino)phenylacetyl)amino)-7-ox o-, (2S-(2-alpha,5-alpha,6-beta(S*)))-
- CAS REGISTRY NUMBER :
- 61477-96-1
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H27-N5-O7-S
- MOLECULAR WEIGHT :
- 517.61
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,987,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5651 No. of Facilities: 148 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 9665 (estimated) No. of Female Employees: 8470 (estimated)
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 42/43 |
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| Safety Phrases | 36/37 |
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| HS Code | 2941101900 |
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Customs
Synonyms
| Pipercillin |
| (2R,5R,6R)-6-{[(2R)-2-{[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| 6-[[[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid |
| PIPC |
| EINECS 262-811-8 |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo- |
| PIPERACILLIN SODIUM |
| PIPERACILLIN NA |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2R,5R,6R)- |
| Piperacillin anhydrous |
| 6-{[{[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino}(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| MFCD00917471 |
| PIPERAILLIN |
| Pipracil |
