CAS 61-01-8|methopromazine

Introduction：Basic information about CAS 61-01-8|methopromazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	methopromazine
CAS Number	61-01-8	Molecular Weight	314.44500
Density	1.143g/cm3	Boiling Point	461.8ºC at 760 mmHg
Molecular Formula	C₁₈H₂₂N₂OS	Melting Point	/
MSDS	/	Flash Point	233.1ºC

Names

Name	3-(2-methoxyphenothiazin-10-yl)-N,N-dimethylpropan-1-amine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.143g/cm3
Boiling Point	461.8ºC at 760 mmHg
Molecular Formula	C₁₈H₂₂N₂OS
Molecular Weight	314.44500
Flash Point	233.1ºC
Exact Mass	314.14500
PSA	41.01000
LogP	4.31460
Index of Refraction	1.603

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SO7600000

CHEMICAL NAME :: Phenothiazine, 10-(3-(dimethylamino)propyl)-2-methoxy

CAS REGISTRY NUMBER :: 61-01-8

LAST UPDATED :: 198209

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H22-N2-O-S

MOLECULAR WEIGHT :: 314.48

WISWESSER LINE NOTATION :: T C666 BN ISJ B3N1&1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 730 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 408 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960 *** REVIEWS *** TOXICOLOGY REVIEW JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 106,755,1960

Synonyms

2-Methoxypromazine

Methopromazinum [INN-Latin]

Neoproma

[3-(2-methoxy-phenothiazin-10-yl)-propyl]-dimethyl-amine

RP 4632

Methoxypromazine

Tentone

2-Methoxy-10-(3'-dimethylaminopropyl)phenothiazine

Methopromazine

Tenton

Methopromazin

Metopromazina [INN-Spanish]

Levopromazine

[3-(2-Methoxy-phenothiazin-10-yl)-propyl]-dimethyl-amin

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