CAS 3952-78-1|alizarin complexone

Introduction：Basic information about CAS 3952-78-1|alizarin complexone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. alizarin complexone BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles34
8. Synonyms

Common Name	alizarin complexone
CAS Number	3952-78-1	Molecular Weight	385.324
Density	1.6±0.1 g/cm3	Boiling Point	687.1±55.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₅NO₈	Melting Point	~185 °C (dec.)
MSDS	ChineseUSA	Flash Point	369.4±31.5 °C

Names

Name	alizarin complexone
Synonym	More Synonyms

alizarin complexone BiologicalActivity

Description	Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor[1][2].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Reverse Transcriptase
References	[1]. Higuchi H, et al. Antiretroviral activities of anthraquinones and their inhibitory effects on reverse transcriptase. Antiviral Res. 1991;15(3):205-216. [2]. Oshima T, et al. Selective extraction of histidine derivatives by metal affinity with a copper(II)-chelating ligand complex in an aqueous two-phase system. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;990:73-79.

Description

Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor[1][2].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Reverse Transcriptase

References

[1]. Higuchi H, et al. Antiretroviral activities of anthraquinones and their inhibitory effects on reverse transcriptase. Antiviral Res. 1991;15(3):205-216.

[2]. Oshima T, et al. Selective extraction of histidine derivatives by metal affinity with a copper(II)-chelating ligand complex in an aqueous two-phase system. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;990:73-79.

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	687.1±55.0 °C at 760 mmHg
Melting Point	~185 °C (dec.)
Molecular Formula	C₁₉H₁₅NO₈
Molecular Weight	385.324
Flash Point	369.4±31.5 °C
Exact Mass	385.079773
PSA	152.44000
LogP	3.38
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.720
InChIKey	PWIGYBONXWGOQE-UHFFFAOYSA-N
SMILES	O=C(O)CN(CC(=O)O)Cc1cc2c(c(O)c1O)C(=O)c1ccccc1C2=O
Stability	Incompatible with strong oxidizing agents.
Water Solubility	Slightly soluble (0.2 g/L)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH0585000

CHEMICAL NAME :: Acetic acid, (((3,4-dihydroxy-2-anthraquinonyl)methyl)imino)di-

CAS REGISTRY NUMBER :: 3952-78-1

BEILSTEIN REFERENCE NO. :: 2190028

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H15-N-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 28,180,1972

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AH0585000
HS Code	2922509090

Customs

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles34

[Histochemical staining methods for lanthanum].

Rinsho Byori. 59(9) , 844-51, (2011)

In recent years lanthanum compounds have been widely used in the optical and electronic industries. Although release of lanthanum (La) into the environment and exposure to humans are feared, acute or ...

Isometric Scaling in Developing Long Bones Is Achieved by an Optimal Epiphyseal Growth Balance.

PLoS Biol. 13 , e1002212, (2015)

One of the major challenges that developing organs face is scaling, that is, the adjustment of physical proportions during the massive increase in size. Although organ scaling is fundamental for devel...

Prostate cancer cells preferentially home to osteoblast-rich areas in the early stages of bone metastasis: evidence from in vivo models.

J. Bone Miner Res. 29(12) , 2688-96, (2014)

It has been suggested that metastasis-initiating cells gain a foothold in bone by homing to a metastastatic microenvironment (or "niche"). Whereas the precise nature of this niche remains to be establ...

Synonyms

2-[carboxymethyl-[(3,4-dihydroxy-9,10-dioxoanthracen-2-yl)methyl]amino]acetic acid

Alizarin-3-methylimino-N,N-diacetic Acid

Glycine, N-(carboxymethyl)-N-[(9,10-dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl]-

Alizarin-3-methyliminodiacetic acid

3,4-Dihydroxyanthraquinon-2-yl-methylimino-diacetic acid

EINECS 223-544-2

MFCD00001202

Alizarin complexone

1,2-Dihydroxyanthraquinonyl-3-methylamine-N,N-diacetic Acid

2,2'-{[(3,4-Dihydroxy-9,10-dioxo-9,10-dihydro-2-anthracenyl)methyl]imino}diacetic acid

2,2'-{[(3,4-Dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl)methyl]imino}diacetic acid

Alizarin Fluorine Blue

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