CAS 136661-76-2|Defensin HNP-3 (human) trifluoroacetate salt

Introduction:Basic information about CAS 136661-76-2|Defensin HNP-3 (human) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDefensin HNP-3 (human) trifluoroacetate salt
CAS Number136661-76-2Molecular Weight3486.04
Density/Boiling Point/
Molecular FormulaC151H222N44O40S6Melting Point/
MSDS/Flash Point/

Names

Nameα-DEFENSIN-3 (HUMAN)
SynonymMore Synonyms

BiologicalActivity

DescriptionDefensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial
References

[1]. Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9.  

[2]. Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435.

Chemical & Physical Properties

Molecular FormulaC151H222N44O40S6
Molecular Weight3486.04
Exact Mass3439.51000
PSA1474.93000
LogP6.05340

Synonyms

Defensin HNP-3 (human)
CAS 30892-86-5|Bradykinin potentiator B
CAS 292633-16-0|Ac-Leu-Glu-His-Asp-AMC trifluoroacetate salt
Recommended......
TOP