Introduction:Basic information about CAS 136661-76-2|Defensin HNP-3 (human) trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Defensin HNP-3 (human) trifluoroacetate salt |
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| CAS Number | 136661-76-2 | Molecular Weight | 3486.04 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C151H222N44O40S6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | α-DEFENSIN-3 (HUMAN) |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Valore EV, et al. Intramolecular inhibition of human defensin HNP-1 by its propiece. J Clin Invest. 1996 Apr 1;97(7):1624-9. [2]. Ganz T, et al. Defensins. Natural peptide antibiotics of human neutrophils[J]. The Journal of clinical investigation, 1985, 76(4): 1427-1435. |
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Chemical & Physical Properties
| Molecular Formula | C151H222N44O40S6 |
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| Molecular Weight | 3486.04 |
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| Exact Mass | 3439.51000 |
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| PSA | 1474.93000 |
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| LogP | 6.05340 |
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Synonyms