CAS 135558-11-1|Lobaplatin

Introduction:Basic information about CAS 135558-11-1|Lobaplatin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameLobaplatin
CAS Number135558-11-1Molecular Weight395.31300
Density/Boiling Point179.5ºC at 760 mmHg
Molecular FormulaC9H16N2O3PtMelting Point220ºC
MSDS/Flash Point75.1ºC

Names

NamePlatinum, [rel-(1R,2R)-1,2-cyclobutanedimethanamine-.kappa.N,.kappa.N'][(2S)-2-(hydroxy-.kappa.O)propanoato(2-)-.kappa.O]-, (SP-4-3)- (9CI) (CA INDEX NAME)

Lobaplatin BiologicalActivity

DescriptionLobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981.

[2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.

Chemical & Physical Properties

Boiling Point179.5ºC at 760 mmHg
Melting Point220ºC
Molecular FormulaC9H16N2O3Pt
Molecular Weight395.31300
Flash Point75.1ºC
Exact Mass395.08100
PSA75.27000
LogP0.53800
Vapour Pressure0.937mmHg at 25°C
Storage condition2-8°C
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