Introduction：Basic information about CAS 161877-70-9|DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt |
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| CAS Number | 161877-70-9 | Molecular Weight | 1233.39 |
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| Density | 1.38g/cm3 | Boiling Point | / |
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| Molecular Formula | C61H76N12O14S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Caspase 1 (ICE) substrate for FRET assays,DABCYL-YVADAPV-EDANS |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1]. |
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| Related Catalog | Research Areas >>Others |
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| References | [1]. Schulz JB, et al. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996 Aug 1;16(15):4696-706. |
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Chemical & Physical Properties
| Density | 1.38g/cm3 |
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| Molecular Formula | C61H76N12O14S |
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| Molecular Weight | 1233.39 |
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| Exact Mass | 1232.53000 |
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| PSA | 384.28000 |
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| LogP | 7.91240 |
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| Index of Refraction | 1.654 |
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Synonyms
| DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS |
| INTERLEUKIN-1BETA CONVERTING ENZYME SUBSTRATE II |
| ICE SUBSTRATE II |
| PASE 1 (ICE) SUBSTRATE |
| 4-(4'-dimethylaminophenylazo)benzoyl-tyrosyl-valyl-alanyl-aspartyl-alanyl-prolyl-valyl-5((2-aminoethyl)amino)naphthalene-1-sulfonic acid |
| DABCYL-YVADAPV-EDANS |
| 4-(4-DIMETHYLAMINOPHENYLAZO)BENZOYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-5-[(2-AMINOETHYL)AMINO]-NAPHTHALENE-1-SULFONIC ACID |
| Caspase 1 (ICE) substrate for FRET assays |
| IL-1B CONVERTING ENZYME SUBSTRATE II |
