Introduction：Basic information about CAS 1674-62-0|1-Methylbiguanide monohydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1-Methylbiguanide monohydrochloride |
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| CAS Number | 1674-62-0 | Molecular Weight | 151.59800 |
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| Density | 1.45g/cm3 | Boiling Point | 295.3ºC at 760mmHg |
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| Molecular Formula | C3H10ClN5 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 132.4ºC |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 1-Methylbiguanide monohydrochloride |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.45g/cm3 |
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| Boiling Point | 295.3ºC at 760mmHg |
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| Molecular Formula | C3H10ClN5 |
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| Molecular Weight | 151.59800 |
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| Flash Point | 132.4ºC |
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| Exact Mass | 151.06200 |
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| PSA | 97.78000 |
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| LogP | 1.10720 |
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| Vapour Pressure | 0.00154mmHg at 25°C |
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| Index of Refraction | 1.624 |
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| InChIKey | AAYCPBAOUJRPIC-UHFFFAOYSA-N |
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| SMILES | CN=C(N)N=C(N)N.Cl |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DU2042000
- CHEMICAL NAME :
- Biguanide, 1-methyl-, monohydrochloride
- CAS REGISTRY NUMBER :
- 1674-62-0
- LAST UPDATED :
- 198702
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C3-H9-N5.Cl-H
- MOLECULAR WEIGHT :
- 151.63
- WISWESSER LINE NOTATION :
- MUYZMYUM&M1 &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1754 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 15,521,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 15,521,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,314,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 470 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,117,1974
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Precautionary Statements | P301 + P312 + P330 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| 1-(diaminomethylidene)-2-methylguanidine,hydrochloride |
| Metformin Related Compound B |
| 1-Methylbiguanide hyrdochloride (Metformin RCB) |
| Metformin Impurity 5(HCl) |
