Introduction：Basic information about CAS 963-14-4|Sulfaethoxypyridazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sulfaethoxypyridazine |
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| CAS Number | 963-14-4 | Molecular Weight | 294.33000 |
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| Density | 1.416g/cm3 | Boiling Point | 565.9ºC at 760mmHg |
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| Molecular Formula | C12H14N4O3S | Melting Point | 182-184ºC |
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| MSDS | USA | Flash Point | 296ºC |
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Names
| Name | 4-amino-N-(6-ethoxypyridazin-3-yl)benzenesulfonamide |
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| Synonym | More Synonyms |
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Sulfaethoxypyridazine BiologicalActivity
| Description | Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | Antibacterial[1] |
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| In Vivo | Feeding of Sulfaethoxypyridazine, a long-acting sulfonamide, to rats at dietary levels of 800, 1600, and 3200 ppm resulted in the development of characteristic lens opacities by 23 weeks. Daily oral administration of 30, 67, and 150 mg/kg to dogs resulted in the development of similar cataracts by 14 weeks[1]. |
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| References | [1]. Ribelin WE, et al. Development of cataracts in dogs and rats from prolonged feeding of sulfaethoxypyridazine. Toxicol Appl Pharmacol. 1967 May;10(3):557-64. |
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Chemical & Physical Properties
| Density | 1.416g/cm3 |
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| Boiling Point | 565.9ºC at 760mmHg |
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| Melting Point | 182-184ºC |
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| Molecular Formula | C12H14N4O3S |
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| Molecular Weight | 294.33000 |
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| Flash Point | 296ºC |
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| Exact Mass | 294.07900 |
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| PSA | 115.58000 |
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| LogP | 2.99330 |
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| Index of Refraction | 1.632 |
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| InChIKey | FFJIWWBSBCOKLS-UHFFFAOYSA-N |
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| SMILES | CCOc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- WO9410000
- CHEMICAL NAME :
- Sulfanilamide, N(sup 1)-(6-ethoxy-3-pyridazinyl)-
- CAS REGISTRY NUMBER :
- 963-14-4
- BEILSTEIN REFERENCE NO. :
- 0286161
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H14-N4-O3-S
- MOLECULAR WEIGHT :
- 294.36
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16240 mg/kg/29W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 30450 mg/kg/29W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| RTECS | WO9410000 |
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| HS Code | 2935009090 |
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Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Articles1
More Articles
| Analysis of sulfonamides, trimethoprim, fluoroquinolones, quinolones, triphenylmethane dyes and methyltestosterone in fish and shrimp using liquid chromatography-mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 972 , 38-47, (2014) A liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method is described for the detection and identification of 26 veterinary drugs in fish and other aquaculture products. The analyt... | |
Synonyms
| Cysul |
| EINECS 213-514-7 |
| 3-Sulfanilylamino-6-aethoxy-pyridazin |
| 6-Aethoxy-3-sulfanilamino-pyridazin |
| SULFAETHOXYPYRIDAZINE |
