CAS 31078-12-3|Alytesin TFA

Introduction:Basic information about CAS 31078-12-3|Alytesin TFA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAlytesin TFA
CAS Number31078-12-3Molecular Weight1535.77000
Density/Boiling Point/
Molecular FormulaC68H106N22O17SMelting Point/
MSDS/Flash Point/

Names

NameAlytesin
SynonymMore Synonyms

Alytesin TFA BiologicalActivity

DescriptionAlytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks[1][2][3]
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Guglietta A, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81.  

[2]. Erspamer V, et al. Some pharmacological actions of alytesin and bombesin. J Pharm Pharmacol. 1970 Nov;22(11):875-6.  

[3]. Cline MA, et al. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91.  

Chemical & Physical Properties

Molecular FormulaC68H106N22O17S
Molecular Weight1535.77000
Exact Mass1534.78000
PSA645.48000
LogP2.06950
InChIKeyISGGITPLKHZHOL-TXYKKBLVSA-N
SMILESCSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C1CCC(=O)N1)C(C)O)C(C)C)C(N)=O

Safety Information

WGK Germany3

Synonyms

pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
pE-GRLGTQWAVGHLM-NH2
GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
PYR-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
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