Introduction：Basic information about CAS 3343-39-3|2-Pyridylethylamine dihydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Pyridylethylamine dihydrochloride |
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| CAS Number | 3343-39-3 | Molecular Weight | 195.09 |
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| Density | 1.025g/cm3 | Boiling Point | 207.9ºC at 760mmHg |
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| Molecular Formula | C7H12Cl2N2 | Melting Point | / |
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| MSDS | / | Flash Point | 100.6ºC |
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Names
| Name | 2-pyridin-2-ylethanamine,dihydrochloride |
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| Synonym | More Synonyms |
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2-Pyridylethylamine dihydrochloride BiologicalActivity
| Description | 2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Souza-Silva E, et al. Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model. Brain Res. 2020 May 15;1735:146757. |
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Chemical & Physical Properties
| Density | 1.025g/cm3 |
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| Boiling Point | 207.9ºC at 760mmHg |
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| Molecular Formula | C7H12Cl2N2 |
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| Molecular Weight | 195.09 |
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| Flash Point | 100.6ºC |
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| Exact Mass | 194.03800 |
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| PSA | 38.91000 |
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| LogP | 2.88710 |
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| InChIKey | GPIFKSYYILNJNR-UHFFFAOYSA-N |
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| SMILES | Cl.Cl.NCCc1ccccn1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- US1819170
- CHEMICAL NAME :
- Pyridine, 2-(2-aminoethyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 3343-39-3
- LAST UPDATED :
- 198712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H10-N2.2Cl-H
- MOLECULAR WEIGHT :
- 195.11
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 30,178,1967
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Synonyms
| 2-PYRIDINEETHANAMINE DIHYDROCHLORIDE |
| 2-Pyridylethylamine dihydrochloride |
| C7H10N2.2HCl |
