CAS 163564-58-7|Kadsulignan N

Introduction：Basic information about CAS 163564-58-7|Kadsulignan N, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Kadsulignan N BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Kadsulignan N
CAS Number	163564-58-7	Molecular Weight	430.491
Density	1.1±0.1 g/cm3	Boiling Point	545.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₀O₇	Melting Point	/
MSDS	/	Flash Point	217.0±30.0 °C

Names

Name	(1R,14S,15S,16R)-4,5,6,9,10,11-Hexamethoxy-15,16-dimethyl-17-oxatetracyclo[12.2.1.02,7.08,13]heptadeca-2,4,6,8,10,12-hexaene
Synonym	More Synonyms

Kadsulignan N BiologicalActivity

Description	Kadsulignan N, a natural product has anti-HIV activity (EC50: 43.56 μM). Kadsulignan N is also a COX-2 ligand (Ki: 72.24 nM)[1][2].
Related Catalog	Signaling Pathways >>Anti-infection >>HIVResearch Areas >>InfectionResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX
Target	COX-2
In Vitro	Kadsulignans N 对 COX-2 表现出较弱的抑制活性，IC50值为 600.54 μM[2]。
References	[1]. Gao XM, et al. Lignans from Kadsura angustifolia. J Nat Prod. 2008 Apr;71(4):558-63. [2]. Zhang XY, et al. Discovery of cyclooxygenase-2 inhibitors from Kadsura coccinea by affinity ultrafiltration mass spectrometry and the anti-inflammatory activity. Fitoterapia. 2021 Jun;151:104872.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	545.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₀O₇
Molecular Weight	430.491
Flash Point	217.0±30.0 °C
Exact Mass	430.199158
PSA	64.61000
LogP	4.24
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.535

Synonyms

(1R,14S,15S,16R)-4,5,6,9,10,11-Hexamethoxy-15,16-dimethyl-17-oxatetracyclo[12.2.1.0.0]heptadeca-2,4,6,8,10,12-hexaene

5,8-Epoxydibenzo[a,c]cyclooctene, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (5R,6R,7S,8S)-

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