Introduction：Basic information about 4'-METHYLCHRYSOERIOL CAS 4712-12-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4'-METHYLCHRYSOERIOL Basic information
| Product Name: | 4'-METHYLCHRYSOERIOL |
| Synonyms: | 5,7-DIHYDROXY-3',4'-DIMETHOXYFLAVONE;CHRYSOERIOL 4'-O-METHYL ETHER;2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one;Luteolin 3',4'-dimethyl ether;Luteolin-3',4'-dimethyl ether;4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-;Rutoside Trihydrate Impurity 13;kampferol-3,4'-dimethyl ether |
| CAS: | 4712-12-3 |
| MF: | C17H14O6 |
| MW: | 314.29 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 4712-12-3.mol |
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4'-METHYLCHRYSOERIOL Chemical Properties
| Melting point | 244 °C (decomp)(Solv: methanol (67-56-1)) |
| Boiling point | 538.3±50.0 °C(Predicted) |
| density | 1.402±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 20.83 mg/mL (66.28 mM);Water : < 0.1 mg/mL (insoluble) |
| pka | 6.49±0.40(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| InChI | InChI=1S/C17H14O6/c1-21-13-4-3-9(5-15(13)22-2)14-8-12(20)17-11(19)6-10(18)7-16(17)23-14/h3-8,18-19H,1-2H3 |
| InChIKey | AOLOMULCAJQEIG-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(OC)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1 |
| LogP | 2.970 (est) |
Safety Information
4'-METHYLCHRYSOERIOL Usage And Synthesis
| Description | 5,7-Dihydroxy-3‘,4’-dimethoxyflavone, also known as 4'-Methylchrysoeriol , is a bioactive Flavonoids found in plants such as Eupatorium odoratum. Studies have shown that 4'-Methylchrysoeriol has death receptor 5 promoter-enhancing activity. |
| Uses | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
| Biological Activity | 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. |
| References | [1] Shimada T, et al. Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res To DOI:10.1021/tx900127s |
4'-METHYLCHRYSOERIOL Preparation Products And Raw materials
