Adenine Sulfate CAS 321-30-2

Introduction：Basic information about Adenine Sulfate CAS 321-30-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Adenine Sulfate Basic information

• Product Name: Adenine Sulfate
• Synonyms: VITAMIN B SULFATE;1H-PURIN-6-AMINE SULFATE;6-AMINOPURINE HEMISULFATE SALT;6-AMINOPURINE SULFATE;ADENINE SULFATE;ADENINE SULPHATE;ADENINE HEMISULFATE;ADENINE HEMISULFATE SALT
• CAS: 321-30-2
• MF: C10H12N10O4S
• MW: 368.33
• EINECS: 206-286-5
• Product Categories: Vitamins and derivatives;Biochemistry;Cytokinins;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Plant Growth Regulators;Pharmaceutical Intermediates;Inhibitors;plantgrowth
• Mol File: 321-30-2.mol

Adenine Sulfate Chemical Properties

• Melting point: 285 °C (dec.)(lit.)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: 0.5 M HCl: 10 mg/mL
• form: powder
• color: White to slightly yellow
• biological source: synthetic (organic)
• Water Solubility: 0.4 g/100 mL
• Sensitive: Hygroscopic
• Merck: 14,152
• BRN: 3820263
• Stability: Hygroscopic
• Major Application: agriculture
• InChI: InChI=1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)
• InChIKey: LQXHSCOPYJCOMD-UHFFFAOYSA-N
• SMILES: C12N=CN=C(N)C=1NC=N2.C12N=CN=C(N)C=1NC=N2.S(=O)(=O)(O)O
• CAS DataBase Reference: 321-30-2(CAS DataBase Reference)
• EPA Substance Registry System: Adenine sulfate (2:1) (321-30-2)

Safety Information

• Hazard Codes: Xn
• Risk Statements: 22-20/21/22
• Safety Statements: 22-24/25-36
• WGK Germany: 3
• RTECS: AU7140000
• F: 8
• TSCA: TSCA listed
• HS Code: 29335990
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral Eye Irrit. 2

Adenine Sulfate Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

Adenine Sulfate has a wide range of chemical and biochemical roles in vivo and in vitro employing as a regulatory molecule. It acts as a precursor, substrate, or cofactor in diverse biochemical pathways.

Uses

Adenine hemisulfate salt has been used as a component of:
complete supplement mixture (CSM)
yeast extract with supplements (YES) medium for culturing S. pombe strain
synthetic complete glucose-based yeast media (SC) for S. cerevisiae cultures

Application

Adenine may be utilized as an additive in plant cell culture. When added to the culture media, such as Murashige & Skoog media, Adenine Sulphate at a concentration of 25mg/L enhances the frequency of multiple shoot production and alleviates chlorotic symptoms of the leaves. This product is suitable for plant tissue culture, as it does not result in any observed structural deformities, toxicity, or necrotic tissues in actively growing shoots or calluses. The recommended culture conditions include an incubation period of 5 weeks, a relative humidity of 60±2%, a temperature of 25±2oC, and a photoperiod of 16 hours of light and 8 hours of darkness.

General Description

Adenine hemisulfate salt is used as a component of minimal medium and yeast extract dextrose, peptone and adenine (YPAD) medium component for culturing yeast.

Biological Activity

Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA.

Biochem/physiol Actions

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and signaling molecules (cAMP).

Synthesis

In a 1000 ml three-necked flask with stirring and reflux device, 177 g of 6-amino-7-acetylpurine and 400 g of 10% sodium hydroxide aqueous solution were added, and the reaction was heated to 80 ?? for 2 hours; then 5 g of activated charcoal was added and the solution was held at a temperature for 1 hour for decoloration, and after decoloration the solution was Filtration, filtrate with mass percentage of 10% hydrochloric acid neutralization to pH 7, cooling solution to 0 ??; and then filtered, the filter cake at 50 ?? drying 10 hours, to get 128 grams of 1H-purin-6-amine, yield 94.8%.