Introduction：Basic information about BOLDINE DIMETHYL ETHER CAS 475-81-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
BOLDINE DIMETHYL ETHER Basic information
| Product Name: | BOLDINE DIMETHYL ETHER |
| Synonyms: | bromcholitin;d-glaucine;glauvent;GLAUCINE;BOLDINE DIMETHYL ETHER;1,2,9,10-TETRAMETHOXYAPORPHINE;(S)-1,2,9,10-TETRAMETHOXY-6-METHYL-5,6,6A,7-TETRAHYDRO-4H-DIBENZO[DE,G]QUINOLINE;(S)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline |
| CAS: | 475-81-0 |
| MF: | C21H25NO4 |
| MW: | 355.43 |
| EINECS: | 207-501-5 |
| Product Categories: | Heterocycles |
| Mol File: | 475-81-0.mol |
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BOLDINE DIMETHYL ETHER Chemical Properties
| Melting point | 246-247℃ |
| alpha | D20 +115° (c = 3 in alc) |
| Boiling point | 488.45°C (rough estimate) |
| density | 1.166±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5614 (estimate) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.35±0.20(Predicted) |
| color | Pale Beige |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
Safety Information
BOLDINE DIMETHYL ETHER Usage And Synthesis
| Description | Glaucine (Item No. 17338) is an analytical reference standard categorized as an antitussive. Glaucine has hallucinogenic properties. This product is intended for research and forensic applications. |
| Uses | d-Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. |
| Definition | ChEBI: (S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups. It has a role as a platelet aggregation inhibitor, a NF-kappaB inhibitor, an antitussive, an antibacterial agent, a muscle relaxant, an antineoplastic agent, a plant metabolite and a rat metabolite. It is an aporphine alkaloid, a polyether, an organic heterotetracyclic compound and a tertiary amino compound. It is a conjugate base of a (S)-glaucine(1+). |
| References | [1] UJVáRY I. Psychoactive natural products: overview of recent developments.[J]. Annali dell’Istituto superiore di sanita, 2014, 50 1: 12-27. DOI: 10.4415/ann_14_01_04
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. |
BOLDINE DIMETHYL ETHER Preparation Products And Raw materials
| Preparation Products | Dehydroglaucine |
