Introduction：Basic information about CINCHOPHEN CAS 132-60-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
CINCHOPHEN Basic information
| Product Name: | CINCHOPHEN |
| Synonyms: | LABOTEST-BB LT00453769;RHEUMIN;RHEMATAN;2-PHENYLQUINOLINE-4-CARBOXYLIC ACID;2-PHENYLQUINOLEINE-4-CARBOXYLIC ACID;2-PHENYLCINCHONINIC ACID;2-PHENYL-4-QUINOLINECARBOXYLIC ACID;CINCHOPHEN |
| CAS: | 132-60-5 |
| MF: | C16H11NO2 |
| MW: | 249.26 |
| EINECS: | 205-067-1 |
| Product Categories: | ATOPHAN;API intermediates;Quinolinecarboxylic Acids, etc.;Quinolines |
| Mol File: | 132-60-5.mol |
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CINCHOPHEN Chemical Properties
| Melting point | 214-215 °C (lit.) |
| Boiling point | 392.37°C (rough estimate) |
| density | 1.1426 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | alcohol: soluble1g in 120ml(lit.) |
| pka | 0.96±0.10(Predicted) |
| form | Solid |
| color | White |
| Water Solubility | Insoluble in water |
| Sensitive | Light Sensitive |
| Merck | 14,2288 |
| BRN | 192803 |
| InChI | 1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19) |
| InChIKey | YTRMTPPVNRALON-UHFFFAOYSA-N |
| SMILES | OC(=O)c1cc(nc2ccccc12)-c3ccccc3 |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36/37/39-26 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | GD4025000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29334990 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 132-60-5(Hazardous Substances Data) |
| Toxicity | LD50 oral in dog: 1250mg/kg |
CINCHOPHEN Usage And Synthesis
| Chemical Properties | BEIGE POWDER |
| Uses | analgesic, antipyretic, antiinflammatory |
| Uses | Cinchophen and its derivatives can show antipyretic, analgesic, anti-oxidative, and anti-inflammatory properties. |
| Definition | ChEBI: 2-phenyl-4-quinolinecarboxylic acid is a member of quinolines. |
| Brand name | Aglophenyl;Alcophenyl;Artexin;Atophan;Cefeno;Cinchophene;Cinconal;Cincosal;Fenofan;Iriphan;Mylofanol;Mylophanol;Phenoquin;Rhematan;Tervalon;Traubofan;Viophan. |
| World Health Organization (WHO) | Cinchophen, an analgesic and antipyretic, was formerly availablein preparations for the treatment of gout. Its use was associated with adverseeffects including hepatitis, cirrhosis, skin lesions and angioneurotic oedema. WHOhas no information to suggest that preparations containing cinchophen remainscommercially available. |
| Purification Methods | It crystallises from EtOH (ca 20mL/g), in several modifications with m 196o and 216o(subliming at 65o). [Beilstein 22 H 103, 22 II 518, 22 II 70, 22 III/IV 1358.] |
CINCHOPHEN Preparation Products And Raw materials
| Raw materials | Acetone-->Sodium formate-->Isatin-->Benzoylformic acid |
