CYCLO(RGDFK(SAA)) CAS 922175-70-0

Introduction：Basic information about CYCLO(RGDFK(SAA)) CAS 922175-70-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

CYCLO(RGDFK(SAA)) Basic information

• Product Name: CYCLO(RGDFK(SAA))
• Synonyms: CYCLO(RGDFK(SAA));GALACTO-RGD;Cyclo(-Arg-Gly-Asp-D-Phe-Lys(SAA));c(RGDfK(SAA));Galacto-RGD,Cyclo(RGDfK(SAA));CYCLO(-ARG-GLY-ASP-D-PHE-LYS((2S,3R,4R,5R,6S)-6-AMINOMETHYL-3,4,5-TRIHYDROXY-TETRAHYDRO-PYRAN-2-CARBONYL));c(RGDfK(galacto));Cyclo[L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-N6-(7-amino-2,6-anhydro-7-deoxy-L-glycero-L-galacto-heptonoyl)-L-lysyl
• CAS: 922175-70-0
• MF: C34H52N10O12
• MW: 792.85
• Mol File: 922175-70-0.mol

CYCLO(RGDFK(SAA)) Chemical Properties

• density: 1.61±0.1 g/cm3(Predicted)
• pka: 4.01±0.10(Predicted)
• Sequence: Cyclo(Arg-Gly-Asp-{d-Phe}-{Lys(SAA)})

CYCLO(RGDFK(SAA)) Usage And Synthesis

Uses

Galacto-RGD is an RGD analogue that can be coupled with the radioactive isotope 18F and used as an integrin α?β? selective tracer[1]. Galacto-RGD can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

References

[1] Ambros J Beer, et al. Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man. Clin Cancer Res. 2006 Jul 1;12(13):3942-9. DOI:10.1158/1078-0432.CCR-06-0266