Fenpyroximate CAS 134098-61-6

Introduction：Basic information about Fenpyroximate CAS 134098-61-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Fenpyroximate Basic information

• Product Name: Fenpyroximate
• Synonyms: 4-[[[[(1,3-Dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]-benzoic acid 1,1-dimethylethyl ester;tert-butyl (e)-4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy)methyl)benzoate;PAMANRIN;ORTUS;1,1-dimethylethylester,(e)-)methyl);4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy)methyl)-,1,1-dimethylethylester,benzoicaci;benzoicacid,4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy;nni850
• CAS: 134098-61-6
• MF: C24H27N3O4
• MW: 421.49
• Mol File: 134098-61-6.mol

Fenpyroximate Chemical Properties

• Melting point: 101.1-102.4°
• Boiling point: 546.2±60.0 °C(Predicted)
• density: 1.25g/cm3
• storage temp.: Store at -20°C
• Water Solubility: Insoluble in water
• solubility: Chloroform: Slightly soluble,Methanol: Slightly soluble
• form: powder to crystal
• pka: 1.58±0.10(Predicted)
• color: White to Light yellow to Light orange
• Stability: Light Sensitive
• Major Application: agriculture environmental
• InChI: 1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+
• InChIKey: YYJNOYZRYGDPNH-MFKUBSTISA-N
• SMILES: Cc1nn(C)c(Oc2ccccc2)c1\C=N\OCc3ccc(cc3)C(=O)OC(C)(C)C
• LogP: 6.443 (est)
• CAS DataBase Reference: 134098-61-6(CAS DataBase Reference)
• EPA Substance Registry System: Fenpyroximate (134098-61-6)

Safety Information

• RIDADR: UN3082 (liquid)
• WGK Germany: WGK 3
• HS Code: 29331990
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 2 Inhalation Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1B
• Hazardous Substances Data: 134098-61-6(Hazardous Substances Data)
• Toxicity: LD50 in male, female rats (mg/kg): 480, 245 orally; >2000, >2000 dermally; LC50 (48hr) in carp: 6.1 mg/l; LC50 (3hr) in daphnia pulex: 85 mg/l (Konno)

Fenpyroximate Usage And Synthesis

Uses

Acaricide.

Definition

ChEBI: Fenpyroximate is a pyrazole acaricide and a tert-butyl ester. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor. It derives from a hydride of a 1H-pyrazole.

Agricultural Uses

Acaricide, Miticide, Insecticide: Used to control spider mites in greenhouses.

Trade name

AKARI®; HOE® 555-02A; NNI®-850;SEQUEL®

Metabolic pathway

When fenpyroximate is administered orally to rats,radiocarbons from 14C-fenpyroximate are rapidly andalmost completely excreted in the urine and feceswithin 72 h, and fenyproximate seems to bemetabolized via oxidation of the tert-butyl group andmethyl group at the 3-position in the pyrazole ring, p-hydroxylation in the phenoxy moiety, N-demethylation,hydrolysis of the tert-butyl ester, cleavage of the oxime ether bond, and/or E/Z isomerization. In soils, 12degradation products are identified, and in sterilizedsoils the degradation of fenpyroximate and CO2,evolution are negligible. Fenpyroximate degradesthrough hydrolysis of tert-butyl ester, isomerization orcleavage of the oxime ether, N-demethylation,oxidation of the methyl group at the 3-position on thepyrazole ring, and hydroxylation of the phenoxy ring,and is finally mineralized to CO2 and/or bound to soilorganic matter.

Fenpyroximate Preparation Products And Raw materials

• Raw materials: Hydroxylamine hydrochloride-->Ethyl acetoacetate-->Methylhydrazine-->Formamide-->Potassium hydroxide solution-->Pyrazole-->4-Bromomethylbenzoic acid-->1,3-Dimethyl-5-pyrazolone-->FORMOXIME