NEUROTENSIN CAS 55508-42-4

Introduction：Basic information about NEUROTENSIN CAS 55508-42-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

NEUROTENSIN Basic information

• Product Name: NEUROTENSIN
• Synonyms: 5-Oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH;Neurotensin【ox】;Neurotensin【rat】;C01836;GLP-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU;Neurotensin, ≥95%(HPLC);NEUROTENSIN;NEUROTENSIN (1-13)
• CAS: 55508-42-4
• MF: C78H121N21O20
• MW: 1672.95
• Product Categories: Peptide
• Mol File: 55508-42-4.mol

NEUROTENSIN Chemical Properties

• density: 1.46±0.1 g/cm3(Predicted)
• storage temp.: -15°C
• pka: 3.41±0.10(Predicted)

NEUROTENSIN Usage And Synthesis

Definition

ChEBI: Neurotensin is a 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. It is a conjugate base of a neurotensin(1+).

General Description

Neurotensin is a 13-amino-acid peptide, first isolated frombovine hypothalamus. It has now been identified in the intestinaltract. The ileal mucosa contains 90% of the total neurotensinof the body. It is implicated as a releasing factor forseveral adenohypophyseal hormones. It causes vasodilatation,increases vascular permeability, and increases gastrinsecretion. It decreases secretion of gastric acid and secretin.