Introduction：Basic information about NEUROKININ A CAS 86933-74-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
NEUROKININ A Basic information
| Product Name: | NEUROKININ A |
| Synonyms: | ALPHA-NEUROKININ;SUBSTANCE K (HUMAN, PORCINE, RAT, MOUSE);SUBSTANCE K;NKA;NEUROKININ A;NEUROKININ A (HUMAN, PORCINE, RAT, MOUSE);NEUROMEDIN L;NEUROMEDIN L (HUMAN, PORCINE, RAT, MOUSE) |
| CAS: | 86933-74-6 |
| MF: | C50H80N14O14S |
| MW: | 1133.33 |
| EINECS: | |
| Product Categories: | Tachykinin receptor;Peptide Receptors;peptide |
| Mol File: | 86933-74-6.mol |
|
NEUROKININ A Chemical Properties
| Boiling point | 1610.7±65.0 °C(Predicted) |
| density | 1.305±0.06 g/cm3(Predicted) |
| RTECS | PC4360090 |
| storage temp. | -20°C |
| form | White to off-white powder. |
| pka | 4.17±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Soluble in water at 1mg/ml |
| Sequence | H-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 |
| InChIKey | HEAUFJZALFKPBA-UHFFFAOYSA-N |
| SMILES | CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O |
Safety Information
| WGK Germany | 3 |
| F | 10-21 |
| Storage Class | 11 - Combustible Solids |
NEUROKININ A Usage And Synthesis
| Uses | Neurokinin A is an endogenous tachykinin agonist with preference for the NK-2R. |
| General Description | Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3. |
| Biochem/physiol Actions | Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer. |
NEUROKININ A Preparation Products And Raw materials
