CAS 61123-13-5|PYR-PHE-PHE-GLY-LEU-MET-NH2

Introduction：Basic information about CAS 61123-13-5|PYR-PHE-PHE-GLY-LEU-MET-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. PYR-PHE-PHE-GLY-LEU-MET-NH2 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	PYR-PHE-PHE-GLY-LEU-MET-NH2
CAS Number	61123-13-5	Molecular Weight	723.88200
Density	1.247g/cm3	Boiling Point	1195.9ºC at 760 mmHg
Molecular Formula	C₃₆H₄₉N₇O₇S	Melting Point	/
MSDS	/	Flash Point	677ºC

Names

Name	[Pyr6]-Substance P (6-11)
Synonym	More Synonyms

PYR-PHE-PHE-GLY-LEU-MET-NH2 BiologicalActivity

Description	[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors[1][2].
Related Catalog	Signaling Pathways >>Neuronal Signaling >>Neurokinin ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Neurokinin Receptor
References	[1]. Brzezinski P M, Godlewski A. The effect of caltitonin, somatostain and analogue (Glp6) of substance P (6-11) on chemotaxis and phagocytosis of guinea pig heterophilis in vitro. Folia Histochemica et Cytobiologica, 1991, 29(4). [2]. Torrens Y, et al. Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder. Neuropeptides. 1997 Jun;31(3):243-51.

Description

[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors[1][2].

Related Catalog

Signaling Pathways >>Neuronal Signaling >>Neurokinin ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Neurokinin Receptor

References

[1]. Brzezinski P M, Godlewski A. The effect of caltitonin, somatostain and analogue (Glp6) of substance P (6-11) on chemotaxis and phagocytosis of guinea pig heterophilis in vitro. Folia Histochemica et Cytobiologica, 1991, 29(4).

[2]. Torrens Y, et al. Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder. Neuropeptides. 1997 Jun;31(3):243-51.

Chemical & Physical Properties

Density	1.247g/cm3
Boiling Point	1195.9ºC at 760 mmHg
Molecular Formula	C₃₆H₄₉N₇O₇S
Molecular Weight	723.88200
Flash Point	677ºC
Exact Mass	723.34100
PSA	242.99000
LogP	3.07390
Index of Refraction	1.579
InChIKey	CTTLAZLIKHEYJW-ZIUUJSQJSA-N
SMILES	CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1)C(N)=O

Synonyms

[PYR1]-SUBSTANCE P (6-11)

Substance P,fragment 6-11,[pGlu6]

pGln-Phe-Phe-Gly-Leu-Met-NH2

PGLU-PHE-PHE-GLY-LEU-MET-NH2

substance P (6-11),pGlu(6)

(PYR6)-SUBSTANCE P (6-11)

SUBSTANCE P [PGLU6]-FRAGMENT 6-11

PYR-PHE-PHE-GLY-LEU-MET-NH2

GLP-PHE-PHE-GLY-LEU-MET-NH2

pyroglutamyl-phenylalanyl-phenylalanine-glycyl-leucyl-methionine amide

[GLP6] SUBSTANCE P (6-11)

(p-Glu6)SP6-11

pglu6-substance P fragment 6-11

[pGlu(6)]-substance P(6-11)

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