Introduction：Basic information about p-Aminobenzamide CAS 2835-68-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
p-Aminobenzamide Basic information
| Product Name: | p-Aminobenzamide |
| Synonyms: | (4-Aminophenyl)carboxamide;4-amino-benzamid;4-Aminobenzenecarboxamide;4-Carbamoylaniline;aminobenzamide;Benzamide, p-amino-;Benzamide,4-amino-;Benzamide,p-amino- |
| CAS: | 2835-68-9 |
| MF: | C7H8N2O |
| MW: | 136.15 |
| EINECS: | 220-612-3 |
| Product Categories: | Azaindoles ,Indolines ,Indoles;Building Blocks;Amides;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;AMIDE;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carbonyl Compounds;Organic Building Blocks;2835-68-9 |
| Mol File: | 2835-68-9.mol |
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p-Aminobenzamide Chemical Properties
| Melting point | 181-183 °C(lit.) |
| Boiling point | 250.42°C (rough estimate) |
| density | 1.1778 (rough estimate) |
| vapor pressure | 0.001-0.001Pa at 25℃ |
| refractive index | 1.5769 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 16.83±0.50(Predicted) |
| form | Crystalline Powder |
| color | Off-white to beige |
| Water Solubility | Slightly soluble in water. |
| BRN | 2079485 |
| InChI | 1S/C7H8N2O/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H2,9,10) |
| InChIKey | QIKYZXDTTPVVAC-UHFFFAOYSA-N |
| SMILES | NC(=O)c1ccc(N)cc1 |
| LogP | -0.38 at 23℃ and pH7 |
| CAS DataBase Reference | 2835-68-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzamide, 4-amino-(2835-68-9) |
| EPA Substance Registry System | Benzamide, 4-amino- (2835-68-9) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/22-36/38-36/37/38 |
| Safety Statements | 38-37/39-26-36 |
| WGK Germany | 1 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29242990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
STOT SE 3 |
p-Aminobenzamide Usage And Synthesis
| Chemical Properties | off-white to beige crystalline powder |
| Uses | 4-Aminobenzamide was used as a poly(ADP-ribose)polymerase (PADPRP) inhhibitor to study the death of target cells by cytotoxic effector cells using the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP). |
| Definition | ChEBI: 4-Aminobenzamide is a member of benzamides. |
| Synthesis Reference(s) | Synthetic Communications, 25, p. 4025, 1995 DOI: 10.1080/00397919508011478 |
p-Aminobenzamide Preparation Products And Raw materials
| Raw materials | Ammonium hydroxide-->Iron-->4-Nitrobenzoic acid-->4-Nitrobenzoyl chloride-->Benzamide, 4,4'-azobis- (8CI,9CI)-->Benzamide, 4-azido--->Benzoyl chloride, 4-amino- (9CI)-->4-BROMOBENZAMIDE-->Ethyl p-nitrobenzoate-->4-Aminoacetophenone-->4-Nitrobenzonitrile-->4-Aminobenzonitrile |
| Preparation Products | Leather Coating Red GL-->Pigment Permanent Red F5RK-->4-Aminobenzylamine-->4-AMINOBENZANILIDE-->4-isothiocyanatobenzamide-->4-AMINO-N-(3,5-DIMETHYLPHENYL)BENZAMIDE |
